Endocrine Abstracts

Background: Parathyroid carcinoma (PC) is a rare cause of primary hyperparathyroidism (PHPT). Distinguishing PC from other tumours underlying PHPT can be difficult and sometimes malignant diagnosis can be made only after recurrence of the disease. Atypical parathyroid adenomas (APA) have similar histological features as PC but lack signs of invasive growth. The expression of somatostatin receptors (SSTR) 1–5 in parathyroid tumours, commonly expressed in other neuroendocri...

Background: Adrenal cortical carcinoma (ACC) is a rare malignancy known to be highly aggressive, with few specific treatment options. The objective was to evaluate clinicopathological features and outcome in patients treated at Helsinki University HospitalMethods and patients: We included all patients diagnosed with adrenocortical carcinoma (Weiss score ≥4) at Helsinki University Hospital during the years 2002 through 2017. Patients were identified...

Introduction and design: Parathyroid carcinoma (PC) is a rare endocrine malignancy and the diagnosis is difficult. As the incidence seems to be increasing, we examined all cases diagnosed in our country during years 2000–2011 and compared the results to those of atypical parathyroid (AA; n=28) and parathyroid adenomas (A; n=72). All tissue specimens were re-examined.Results: In 2000–2011, 32 patients were diagnosed with PC in ...